• Detection Analysis and Study of Genomic Region Variability of JCPyV, BKPyV, MCPyV, HPyV6, HPyV7 and QPyV in the Urine and Plasma of HIV-1-Infected Patients 

      Passerini, Sara; Prezioso, Carla; Prota, Annalisa; Babini, Giulia; Coppola, Luigi; Lodi, Alessandra; Epifani, Anna Chiara; Sarmati, Loredana; Andreoni, Massimo; Moens, Ugo; Pietropaolo, Valeria; Ciotti, Marco (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-17)
      Since it was clearly established that HIV/AIDS predisposes to the infection, persistence or reactivation of latent viruses, the prevalence of human polyomaviruses (HPyVs) among HIV-1-infected patients and a possible correlation between HPyVs and HIV sero-status were investigated. PCR was performed to detect and quantify JCPyV, BKPyV, MCPyV, HPyV6, HPyV7 and QPyV DNA in the urine and plasma samples ...
    • Structural Analysis of Merkel Cell Polyomavirus (MCPyV) Viral Capsid Protein (VP1) in HIV-1 Infected Individuals 

      Prezioso, Carla; Bianchi, Martina; Obregon, Francisco; Ciotti, Marco; Sarmati, Loredana; Andreoni, Massimo; Palamara, Anna Teresa; Pascarella, Stefano; Moens, Ugo; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-27)
      Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates virus attachment to host cell receptors and is the major immune target. Given the limited data on MCPyV VP1 mutations, the VP1 genetic variability was examined in 100 plasma and 100 urine samples from 100 HIV+ individuals. Sequencing of VP1 DNA in 17 urine and 17 plasma specimens, simultaneously MCPyV DNA ...